Prof. Roger Tsien was born in New York on February 1, 1952. He is an American Biochemist and a Professor at the department of Chemistry and Biochemistry, University of California, San Diego. When he was 16, he won the first prize in the Nationwide Westinghouse talent search with a “project investigating how metals bind to thiocyanate”. He attended Harvard University on a National Merit Scholarship, Where he was elected to Phi Beta Kappa as a junior. He received his undergraduate degree in Chemistry and Physics from Summa cum laude 1972 and PhD degree in Physiology from University of Cambridge in 1977.Prof. Tsien was a Research Fellow at Gonville and Caius college, University of Cambridge from 1977 to 1981.He served the University of California, Berkeley, from 1982 to 1989.Since 1989 he has been working at the University of California, san Diego, as a professor of Pharmacology and a Professor of Chemistry and biochemistry, and an investigator of the Howard Hughes Medical Institute. Prof. Tsien is renowned for revolutionizing the fields of cell biology and neurobiology by allowing Scientists to peer inside living cells and watch the behavior of molecules in real time. Prof. Tsien is a key pioneer of calcium imaging and well-known for developing various colorful dyes such as Fura-2, is widely used to track the movement of calcium within the cells and has genetically modified organism to produce the molecules that make jellyfish and corals glow, creating fluorescent colors in a dazzling variety of hues. Indo-1, another popular calcium indicator, was also developed by Tsien’s group in 1985.In 2004, Prof. Tsien was awarded the Wolf Prize in Medicine “for his seminal contribution to the design and biological application of novel fluorescent and photo liable molecules to analyze and perturb cell signal transduction”. He was awarded the 2008 Nobel Prize in Chemistry “for his discovery and development of the Green Fluorescent Protein (GFP)” with two other Chemists: Martin Chalfie of Columbia University and Osamu Shimomura of Boston University and Marine Biological laboratory.